The ARH-77 cell line was established from the peripheral blood of a patient suffering from IgG plasma cell leukemia. Although established from cells taken from a patient with a plasma cell leukemia, this line has been shown to be an EBV-transformed B lymphoblastoid cell line.
Species:
Homo sapiens, human
Tissue:
peripheral blood
Disease:
plasma cell leukemia
Gender:
Caucasian,female, 33 years
Morphology:
lymphoblast
Growth Mode:
suspension
DNA Profile:
D5S818: 10,13
D13S317: 11,13
D7S820: 7,12
D16S539: 9,13
vWA: 17
THO1: 8,9.3
Amelogenin: X
TPOX: 8
CSF1PO: 6,10
Our Cell Line Authentication Service
The cells are positive for Epstein-Barr nuclear antigen(EBNA +) and Epstein-Barr viral capsid antigen (EBVCA +). The line has been cured of a previous mycoplasma infection.LICR-LON-HMy2 (HMy2), a fast growing mutant of the ARH-77 cell line (ATCC CRL-1621), was irradiated and selected for class I loss to establish the HMy2.C1R (ATCC CRL-1993) cell line. Subsequently, C1R-neo (ATCC CRL-2369), C1R-sB7 (ATCCCRL-2370), and C1R-B7 (ATCC CRL-2371) were established by transfection of the HMy2.C1R cell line.
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