Dectin1b Effector Reporter Cell(Adherent)
CBP74550
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產(chǎn)品描述
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| I. Background | |
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Dectin1b 是 Dectin-1 受體的一個(gè)亞型（Isoform B），屬于C型凝集素受體家族。它主要表達(dá)于髓系免疫細(xì)胞表面，作為模式識(shí)別受體特異性識(shí)別真菌細(xì)胞壁成分β-葡聚糖，在啟動(dòng)抗真菌免疫應(yīng)答中發(fā)揮核心作用。 |
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| II. Description | |
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Dectin1b Effector Reporter Cell(Adherent)報(bào)告基因藥靶模型很好的模擬了體內(nèi) Dectin1b 的信號(hào)轉(zhuǎn)導(dǎo)過(guò)程。 |
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| III. Introduction | |
| Expressed gene: | Dectin1b |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | MEM+10%FBS + 1% NEAA+ 1mM NaP+ 1 μg/ml Puromycin+ 100 μg/ml Hygromycin B+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
IV. Representative Data Figure 1. Recombinant Dectin1b Effector Reporter Cell stably expressing Dectin1b.  Figure 2. Dose Response of Ligands in Dectin-1b Effector Reporter Cell(Adherent, C35). |
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